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Senior Scientist I/II, Biological Sciences

Company: Deciphera Pharmaceuticals
Location: Lawrence
Posted on: November 24, 2022

Job Description:

Company Description
Deciphera is a biopharmaceutical company focused on discovering, developing and commercializing important new medicines to improve the lives of people with cancer. We are leveraging our proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines.
In addition to advancing multiple product candidates from our platform in clinical studies, QINLOCK - is Deciphera's FDA-approved switch-control kinase inhibitor for the treatment of fourth-line gastrointestinal stromal tumor (GIST). QINLOCK is also approved for fourth-line GIST in Australia, Canada, China, and Hong Kong.
Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered in Waltham, Massachusetts. Our state-of-the-art research facility is located in Lawrence, Kansas.
We offer an outstanding culture and opportunity for personal and professional growth based on our "PATHS" Core Values:
Patients - places the importance of improving the lives of patients and their caregivers at the forefront of every day's work.
Accountability - for our performance and the way we work with coworkers and other stakeholders.
Transparency - in our intent and actions to both internal and external stakeholders.
Honesty and Integrity - fosters trust and strives to deliver on our and the company's promises.
Stewardship - values and uses wisely the resources and investments provided to the company.
Job Description
We are seeking a collaborative, highly motivated and self-driven Senior Scientist I/II to join our Biological Sciences drug discovery group. This position will work with the Biological Sciences team to discover new kinase inhibitors for the treatment of cancer.
This position will report to a Senior Principal Investigator and is located in our state-of-the-art research facility near the University of Kansas in Lawrence, Kansas.
What You'll Do

  • Responsible for independently developing and validating new molecular biology and cell-based assays needed to understand activities of kinase inhibitors in cancer cells and cells found in the tumor microenvironment
  • Generate transient and stable-transfected cell lines needed to understand activities of kinase inhibitors
  • Perform routine mammalian cell culture
  • Perform routine screening of small molecule kinase inhibitors
  • Collaborate with advisor on managing external pharmacology studies
  • Responsible for analysis of samples from studies performed at CROs
  • Keeps abreast of relevant literature and contributes to the identification and validation of new drug targets
  • Responsible for tracking and recording data into corporate database and notebooks
  • Responsible for effectively working in a team environment, communicating and planning research with others also working on project
  • Acts as a mentor to Junior scientists
  • Responsible for adhering to corporate policies including safety, FDA compliance and regulatory matters
  • Responsible for generating reports and presentations as required by the organization
  • Participate in the preparation of scientific abstracts and manuscripts
  • Perform other research duties when requested
  • Able to independently work in a fast-paced environment
  • Values other people and promotes the welfare of the organization and colleagues
    • PhD in Molecular Biology, Biochemistry or a related field with 2-4 years of research experience. MS with > 8 years of research experience. Experience in biotech or pharmaceutical industry, particularly in the fields of drug discovery and oncology, preferred
    • Technical skills required: laboratory experience with enzyme, cell biology and immunology techniques
    • Adaptability and capability to work on multiple drug programs simultaneously
    • Other: Computer skills with MS Office (Excel, Word, PPT) and scientific graphing software
      Additional Information
      What Deciphera will Bring:
      Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes the following:
      • Summer vacation bonus
      • Global, company-wide summer and winter shutdowns
      • An annual lifestyle allowance
      • Internal rewards and recognition program
        Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered in Waltham, Massachusetts. Our state-of-the-art research facility is located in Lawrence, Kansas and our European operations are run out of Switzerland.
        Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements and to learn more about how we can increase diversity in our candidate pool, we invite you to voluntarily provide demographic information in a confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. Our commitment to increasing diversity in our candidate pool does not affect our commitment to equal employment opportunity, including our ongoing commitment to make all hiring and other employment decisions solely on a nondiscriminatory basis.

Keywords: Deciphera Pharmaceuticals, Lawrence , Senior Scientist I/II, Biological Sciences, Other , Lawrence, Kansas

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